Fildena

Fildena is a prescription medication specifically formulated to address erectile dysfunction (ED) by enhancing blood flow to the penis, facilitating the achievement and maintenance of an erection sufficient for sexual activity. Its active ingredient, Sildenafil Citrate, is a well-established phosphodiesterase type 5 (PDE5) inhibitor, clinically proven to be a reliable first-line treatment for this common condition. By targeting the underlying physiological mechanisms of erection, Fildena offers a targeted solution for men seeking to regain sexual vitality and improve their intimate relationships. This product card provides a comprehensive, expert-level overview of its use, benefits, and essential safety information.

Features

• Active Pharmaceutical Ingredient: Sildenafil Citrate
• Available Strengths: 25 mg, 50 mg, 100 mg, 120 mg, 150 mg, and 200 mg film-coated tablets
• Pharmacological Class: Selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5)
• Onset of Action: Typically within 30-60 minutes post-administration
• Duration of Effect: Efficacy can last for up to 4-6 hours
• Administration: Oral, with or without food (though high-fat meals may delay absorption)

Benefits

• Reliable Erection Achievement: Effectively facilitates the physical response to sexual stimulation, enabling a firm erection.
• Sustained Performance Support: Provides a sufficient window of opportunity for spontaneous and satisfactory sexual activity.
• Improved Self-Esteem and Relationship Quality: Successfully managing ED can significantly reduce anxiety and improve overall confidence and intimacy.
• Proven Clinical Efficacy: As a generic form of Sildenafil, it is backed by extensive clinical research and decades of real-world use.
• Dosage Flexibility: Multiple available strengths allow for personalized treatment plans tailored to individual efficacy and tolerability.

Common use

Fildena is primarily indicated for the treatment of erectile dysfunction (ED) in adult men. Erectile dysfunction is defined as the consistent or recurrent inability to achieve and/or maintain a penile erection sufficient for satisfactory sexual performance. It is not an aphrodisiac and does not increase libido; sexual stimulation is required for the medication to be effective. Its use is based on a proper medical diagnosis to ensure it is an appropriate therapeutic option.

Dosage and direction

The dosage of Fildena must be determined by a healthcare professional based on the patient’s health status, tolerance, and efficacy.

• Standard Starting Dose: The recommended starting dose for most patients is 50 mg, taken approximately one hour before anticipated sexual activity.
• Dose Adjustment: Based on effectiveness and side effects, the dose may be increased to a maximum of 100 mg or decreased to 25 mg.
• Higher Strengths (120 mg, 150 mg, 200 mg): These are typically reserved for patients who do not achieve a satisfactory response with the 100 mg dose and are prescribed under close medical supervision due to an increased risk of side effects.
• Frequency: Fildena should not be taken more than once per day.
• Administration: The tablet should be swallowed whole with a glass of water. It can be taken with or without food. However, taking it after a high-fat meal may delay the time it takes for the medication to start working.

Precautions

• Cardiovascular Health: Sexual activity poses a potential cardiac risk. Fildena should not be used by men for whom sexual activity is inadvisable due to underlying cardiovascular problems. A thorough cardiovascular assessment is recommended prior to initiating any treatment for ED.
• Priapism: Prolonged and sometimes painful erections lasting more than 4 hours can occur. This is a medical emergency that requires immediate treatment to avoid long-term damage to the penile tissues. Seek immediate medical attention if an erection persists beyond 4 hours.
• Vision and Hearing Changes: Sudden decrease or loss of vision in one or both eyes, or sudden decrease or loss of hearing, have been reported rarely. These events warrant immediate discontinuation of the drug and urgent medical evaluation.
• Underlying Medical Conditions: Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, or Peyronie’s disease), bleeding disorders, active peptic ulceration, or those who have undergone radical prostatectomy.
• Alcohol and Grapefruit: Heavy consumption of alcohol can increase the risk of side effects like dizziness and orthostatic hypotension. Grapefruit and grapefruit juice may interact with Fildena and increase the concentration of the drug in your bloodstream, increasing the risk of adverse effects; concurrent use is not recommended.

Contraindications

Fildena is absolutely contraindicated in the following scenarios:

• Concomitant use of any form of organic nitrates (e.g., nitroglycerin, isosorbide mononitrate or dinitrate) or nitric oxide donors in any form. The concomitant administration can lead to a severe, life-threatening drop in blood pressure.
• Concomitant use of guanylate cyclase stimulators such as riociguat (Adempas®), as this also may result in symptomatic hypotension.
• Hypersensitivity to Sildenafil Citrate or any of the excipients in the formulation.
• Patients with severe hepatic impairment.
• Patients with severe hypotension (low blood pressure) or hypertension (high blood pressure) that is not controlled.
• Recent history of stroke or myocardial infarction (heart attack).
• Patients with hereditary degenerative retinal disorders (e.g., retinitis pigmentosa).

Possible side effect

Like all medicines, Fildena can cause side effects, although not everybody gets them. Most are mild to moderate and transient.

Very Common (≥1/10):

• Headache
• Flushing

Common (≥1/100 to <1/10):

• Dyspepsia (indigestion)
• Nasal congestion
• Dizziness
• Visual disturbances (e.g., blurred vision, changes in color perception, increased sensitivity to light)

Uncommon (≥1/1,000 to <1/100):

• Hypotension (low blood pressure)
• Tachycardia (increased heart rate)
• Vomiting
• Muscle aches
• Back pain

Rare (≥1/10,000 to <1/1,000):

• Priapism
• Syncope (fainting)
• Sudden hearing loss
• Non-arteritic anterior ischemic optic neuropathy (NAION) - sudden vision loss

Drug interaction

The potential for drug interactions is significant. Always inform your doctor of all medications you are taking, including prescription, over-the-counter, and herbal products.

• Nitrates: Absolute contraindication. Concomitant use can cause a profound drop in blood pressure, leading to shock, myocardial infarction, or stroke.
• Alpha-blockers (e.g., doxazosin, tamsulosin): Concomitant use can lead to symptomatic hypotension (dizziness, lightheadedness, fainting). Dose adjustment and careful monitoring are required.
• Other Antihypertensives: Fildena may potentiate the blood-pressure-lowering effect of other medications used to treat hypertension.
• Potent CYP3A4 Inhibitors: Drugs like ketoconazole, itraconazole, ritonavir, and clarithromycin can significantly increase Sildenafil plasma concentrations. Dose reduction of Fildena is strongly recommended.
• CYP3A4 Inducers: Drugs like rifampin can decrease Sildenafil plasma concentrations, potentially reducing its efficacy.

Missed dose

Fildena is not intended for daily scheduled use; it is taken on an as-needed basis. Therefore, the concept of a “missed dose” does not apply. Simply take it approximately one hour before planned sexual activity when needed, ensuring you do not exceed one dose in a 24-hour period.

Overdose

In cases of overdose exceeding the maximum recommended dose, the clinical picture would be an exaggeration of the known adverse effects.

• Symptoms: Severe and prolonged headache, profound flushing, dizziness, hypotension, syncope, and potentially prolonged priapism.
• Management: Standard supportive measures should be adopted as required. This includes maintaining hydration and supine positioning to manage hypotension. Renal dialysis is not expected to accelerate clearance as Sildenafil is highly protein-bound and metabolized extensively in the liver. Priapism requires immediate urological intervention.

Storage

• Store below 30°C (86°F).
• Keep the tablets in their original blister pack or bottle to protect from light and moisture.
• Keep out of the sight and reach of children.
• Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here. The information provided has been compiled from various sources believed to be reliable and accurate, but no guarantee, warranty, or representation is made regarding its accuracy or completeness.

Reviews

• “After struggling with ED post-prostate surgery, my urologist prescribed Fildena 100mg. It has reliably restored my ability to have a satisfying sex life. The effect is consistent, and aside from some minor flushing, I’ve had no issues.” – Mark T., 62
• “I was initially skeptical about generic medications, but Fildena has been just as effective as the brand-name version for me at a fraction of the cost. It works within 45 minutes for me and lasts long enough that there’s no pressure to rush.” – James L., 58
• “I experienced a severe headache the first time I took the 50mg dose. My doctor advised me to try taking it with a light meal and plenty of water, which made a huge difference. The headaches are now minimal and well worth the benefit.” – Robert K., 51
• “The flexibility of different dosages is a major plus. We started low and found the 50mg strength is the perfect balance of efficacy and minimal side effects for my husband. It has had a very positive impact on our relationship.” – Sarah P., Partner
• “As a healthcare professional, I appreciate the robust clinical data behind Sildenafil. Choosing Fildena was an evidence-based decision for managing my mild ED. It’s effective, predictable, and I feel confident in its safety profile when used correctly.” – Dr. Evan R., 49