Vidalista

Vidalista Black 80 mg is a high-dose pharmaceutical formulation of Tadalafil, a PDE5 inhibitor clinically proven to manage erectile dysfunction (ED). This medication facilitates increased blood flow to the penile tissues upon sexual stimulation, enabling the achievement and maintenance of an erection sufficient for satisfactory sexual activity. Its extended duration of action distinguishes it from shorter-acting alternatives, offering a significant therapeutic window. Prescribed for adult males, it addresses both physiological and psychological aspects of ED, supporting improved sexual health and confidence.

Features

• Active Pharmaceutical Ingredient: Tadalafil (80 mg)
• Drug Class: Phosphodiesterase type 5 (PDE5) inhibitor
• Standard Onset of Action: Approximately 30-45 minutes post-administration
• Therapeutic Duration: Up to 36 hours
• Administration Route: Oral
• Presentation: Film-coated tablet

Benefits

• Achieves reliable and firm erections responsive to sexual stimulation.
• Provides an extended period of efficacy, reducing time-sensitive pressure and allowing for spontaneity.
• Enhances overall sexual performance and satisfaction for both partners.
• Contributes to improved self-esteem and reduced anxiety related to sexual performance.
• Offers a potent treatment option for men who may not respond adequately to lower doses of Tadalafil or other ED medications.

Common use

Vidalista Black is primarily indicated for the treatment of erectile dysfunction (ED) in adult men. It is used to overcome the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. The medication is taken on an as-needed basis prior to anticipated sexual activity. Its use is contingent upon sexual stimulation; it will not cause an erection spontaneously.

Dosage and direction

The standard dose of Vidalista Black is one 80 mg tablet taken orally, approximately 30-60 minutes before anticipated sexual activity. The tablet should be swallowed whole with a glass of water; it may be taken with or without food, though a high-fat meal may delay the onset of action. The dosing frequency should not exceed once in any 24-hour period. The dosage must be determined by a qualified healthcare professional based on individual patient health, tolerance, and efficacy. Do not adjust the dosage without medical consultation.

Precautions

• Prior to initiation, a thorough medical evaluation is necessary to diagnose ED and assess cardiovascular health, as sexual activity poses a potential cardiac risk.
• Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie’s disease) or conditions predisposing to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia).
• Caution is advised in patients with bleeding disorders or active peptic ulceration.
• This medication can cause hypotension. Exercise caution in patients taking antihypertensives or with underlying cardiovascular conditions.
• Non-arteritic anterior ischemic optic neuropathy (NAION) has been reported post-marketing. Discontinue use immediately and seek medical attention in the event of sudden vision loss in one or both eyes.
• Sudden decrease or loss of hearing has been reported. Seek immediate medical attention if these symptoms occur.

Contraindications

Vidalista Black is strictly contraindicated in the following scenarios:

• Concomitant administration with any form of organic nitrates (e.g., nitroglycerin, isosorbide mononitrate/dinitrate) or nitric oxide donors. This combination can lead to a severe, life-threatening drop in blood pressure.
• Concomitant use with guanylate cyclase stimulators, such as riociguat.
• Patients with a known hypersensitivity to Tadalafil or any of the tablet’s excipients.
• Patients with severe cardiovascular disorders where sexual activity is inadvisable (e.g., unstable angina, severe heart failure, recent myocardial infarction or stroke).
• Patients with severe hepatic impairment (Child-Pugh Class C).

Possible side effects

Like all medicines, Vidalista Black can cause side effects, although not everybody gets them. Side effects are often dose-related and may include:

• Very Common (≥1/10): Headache, dyspepsia.
• Common (≥1/100 to <1/10): Back pain, myalgia, nasal congestion, flushing, dizziness, pain in extremity.
• Uncommon (≥1/1,000 to <1/100): Nausea, vomiting, gastroesophageal reflux disease, visual disturbances (e.g., blurred vision, cyanopsia), tinnitus, palpitations, tachycardia, hypotension, syncope.
• Rare (≥1/10,000 to <1/1,000): Priapism (a prolonged and painful erection lasting more than 4 hours), urticaria, rash.
• Very Rare (<1/10,000): NAION, sudden hearing loss, serious cardiovascular events (e.g., myocardial infarction, stroke, unstable angina pectoris) have been reported in temporal association with Tadalafil use.

Drug interaction

Tadalafil is primarily metabolized by CYP3A4. Concomitant use with the following requires caution or is contraindicated:

• Contraindicated: Organic nitrates (e.g., nitroglycerin, isosorbide mononitrate).
• Use with caution/contraindicated: Guanylate cyclase stimulators (e.g., riociguat).
• Potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin): Can significantly increase Tadalafil exposure. A dose reduction may be required; avoid use with potent inhibitors is advised for this high-dose formulation.
• Alpha-blockers (e.g., doxazosin, tamsulosin): Concomitant use can potentiate the blood-pressure-lowering effects. This combination should be approached with caution and only if the patient is stable on alpha-blocker therapy.
• Antihypertensives: May potentiate the hypotensive effect.
• Alcohol: Excessive consumption can increase the risk of orthostatic hypotension and dizziness.

Missed dose

Vidalista Black is not intended for regular daily dosing but for use as needed. Therefore, the concept of a “missed dose” does not apply. Simply take one tablet when you plan to be sexually active, ensuring at least 24 hours have passed since the last dose. Do not take a double dose to make up for a missed occasion.

Overdose

In cases of suspected overdose, standard supportive measures should be adopted. Expected effects would be an extension of the drug’s known vasodilatory properties, including severe headache, pronounced flushing, dizziness, syncope, and potentially dangerous hypotension. Hemodynamic support may be required. Dialysis is not expected to accelerate clearance as Tadalafil is highly protein-bound. Immediately contact a poison control center or emergency medical services.

Storage

• Store below 30°C (86°F).
• Keep the tablets in the original blister pack to protect from light and moisture.
• Keep out of the sight and reach of children.
• Do not use this medicine after the expiry date printed on the pack.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here. The information provided has been compiled from available data but may not be exhaustive.

Reviews

• “As a urologist, I reserve Vidalista Black for patients with more severe ED who have shown suboptimal response to standard doses. The 36-hour window is a significant advantage for many, reducing performance anxiety. It is a potent tool, but patient selection and counseling on contraindications, especially nitrates, are paramount.” – Dr. Evan R., MD
• “After trying several other medications with limited success, my physician recommended we try this higher dose. The efficacy is undeniable and the extended duration allows for a much more natural and less planned intimate life. The side effects for me were a mild headache and some nasal stuffiness initially, which subsided.” – Mark T., patient
• “The pharmacokinetic profile of high-dose Tadalafil offers a unique position in ED therapy. However, its potency necessitates rigorous adherence to prescribing guidelines. Clinicians must thoroughly evaluate cardiovascular status and potential drug interactions before prescription. It is not a first-line option but a valuable one for specific patient profiles.” – Clinical Pharmacologist Review