Silagra

Silagra is a prescription medication containing sildenafil citrate, a potent phosphodiesterase type 5 (PDE5) inhibitor, specifically formulated for the treatment of erectile dysfunction (ED). It functions by enhancing blood flow to the penile tissues, facilitating the achievement and maintenance of an erection sufficient for satisfactory sexual activity. This pharmaceutical agent is recognized for its high bioequivalence to the brand-name counterpart, offering a therapeutically equivalent option. It is intended for use by adult males and requires sexual stimulation for efficacy. Clinical efficacy is well-documented, making it a reliable choice under appropriate medical guidance.

Features

• Active Pharmaceutical Ingredient: Sildenafil Citrate 100mg
• Pharmacological Class: Phosphodiesterase Type 5 (PDE5) Inhibitor
• Onset of Action: Typically within 30 to 60 minutes post-administration
• Duration of Effect: Efficacy can last for up to 4-6 hours
• Administration: Oral tablet, to be taken with or without food (though high-fat meals may delay absorption)
• Manufacturer Compliance: Produced in facilities adhering to Good Manufacturing Practices (GMP)
• Packaging: Blister packs ensuring stability and protection from moisture

Benefits

• Effectively facilitates the physiological process necessary for achieving and sustaining an erection when combined with sexual stimulation.
• Provides a predictable therapeutic window, allowing for planned sexual activity.
• Offers a cost-effective alternative to brand-name sildenafil without compromising on pharmacological efficacy.
• Supports improved sexual confidence and relationship satisfaction by addressing the underlying vascular component of ED.
• High rate of patient-reported success and tolerability in clinical settings.
• Convenient single-dose administration per intended sexual activity.

Common use

Silagra is primarily indicated for the treatment of erectile dysfunction in adult males. It is used on an as-needed basis to improve erectile function. It is not intended for use by women, children, or adolescents. It does not protect against sexually transmitted infections and is not a form of contraception.

Dosage and direction

The recommended starting dose for most patients is 50mg taken approximately one hour before anticipated sexual activity. Based on efficacy and tolerability, the dose may be increased to a maximum of 100mg or decreased to 25mg. Dosage adjustment is necessary for patients with hepatic impairment, severe renal impairment, or those taking certain concomitant medications (e.g., potent CYP3A4 inhibitors). The tablet should be swallowed whole with a glass of water. Do not take more than one dose in a 24-hour period.

Precautions

Prior to initiating treatment with Silagra, a thorough medical assessment should be conducted to diagnose ED and identify any underlying cardiovascular pathology, as sexual activity carries potential cardiac risk. Use with caution in patients with anatomical deformation of the penis, predisposition to priapism, bleeding disorders, or active peptic ulceration. Patients with cardiovascular conditions such as heart failure, coronary artery disease, or uncontrolled hypertension should be evaluated for suitability before use. Avoid use in patients for whom sexual activity is inadvisable.

Contraindications

Silagra is contraindicated in patients with a known hypersensitivity to sildenafil citrate or any excipients in the formulation. Concomitant administration with organic nitrates or nitric oxide donors in any form is absolutely contraindicated due to the risk of profound hypotension. It is also contraindicated in patients taking guanylate cyclase stimulators, such as riociguat.

Possible side effects

The most commonly reported adverse reactions are headache, flushing, dyspepsia, nasal congestion, and dizziness. These are generally mild to moderate in intensity and transient. Visual disturbances (e.g., changes in color perception, blurred vision) have been reported. Less frequently, patients may experience back pain, myalgia, or nausea. Priapism (a prolonged and painful erection lasting more than 4 hours) is a rare but serious adverse event requiring immediate medical intervention to prevent permanent tissue damage. Sudden decrease or loss of hearing or vision has been reported in temporal association with PDE5 inhibitor use. Discontinue use and seek prompt medical attention if any of these occur.

Drug interaction

Concomitant use with nitrates is contraindicated. Potent inhibitors of the cytochrome P450 3A4 pathway (e.g., ketoconazole, itraconazole, ritonavir) can significantly increase sildenafil plasma concentrations, necessitating dose adjustment. Alpha-blockers may potentiate the blood-pressure-lowering effects. Grapefruit juice may increase plasma levels of sildenafil and should be avoided. Sildenafil may potentiate the hypotensive effects of alcohol.

Missed dose

Silagra is not intended for chronic daily dosing. It is taken on an as-needed basis approximately one hour before sexual activity. Therefore, the concept of a “missed dose” does not apply. Do not take an extra dose to make up for a missed occasion.

Overdose

In cases of suspected overdose, standard supportive measures should be employed. Given its vasodilatory effects, the primary manifestation is likely to be hypotension. Management of hypotension may include placing the patient in the Trendelenburg position and administering intravenous fluids. Dialysis is not expected to accelerate clearance as sildenafil is highly protein-bound.

Storage

Store at room temperature (15°C to 30°C) in the original blister package to protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here.

Reviews

“After discussing options with my urologist, I was prescribed Silagra. The effect is reliable and has significantly improved my quality of life. I experienced mild flushing the first time, but it subsided quickly and hasn’t recurred.” – Patient M, 54 “As a healthcare provider, I find Silagra to be a therapeutically equivalent and cost-effective option for my suitable patients with ED. It is important that patients undergo proper screening and receive clear dosage instructions.” – Dr. A, Urologist “It works exactly as expected. Taking it on an empty stomach seems to make it work faster for me. No notable side effects after several uses.” – Patient R, 61 “I appreciate the clarity of information provided with the medication. It allowed me to have an informed discussion with my doctor about its use with my current medications.” – Patient T, 58