Podowart

Podowart is a topical solution specifically formulated for the targeted treatment of plantar warts, offering a potent and precise approach to a common dermatological concern. Developed with healthcare professionals in mind, this solution provides a reliable, clinician-trusted method for wart removal, combining efficacy with a well-established safety profile. Its active ingredient works by chemically destroying wart tissue, allowing for controlled application and predictable results in both clinical and home-care settings under professional guidance.

Features

• Contains podophyllotoxin as the active ingredient at a concentration of 0.5% w/w
• Presented as a clear, easy-to-apply topical solution
• Supplied in a 3 mL bottle with a precision applicator tip
• Formulated for selective cytotoxicity against wart tissue
• Alcohol-based vehicle for rapid drying and reduced spread to surrounding skin
• Single formulation suitable for common and plantar wart variants

Benefits

• Effectively destroys wart tissue through localized cytotoxic action
• Reduces recurrence rates through complete eradication of affected cells
• Minimizes discomfort compared to ablative procedures
• Allows for precise application to avoid damage to healthy peri-lesional skin
• Enables patient-administered treatment following professional diagnosis and instruction
• Provides a cost-effective alternative to repeated clinical interventions for multiple or recurrent warts

Common use

Podowart is primarily indicated for the treatment of benign epithelial growths caused by human papillomavirus (HPV), specifically common warts (verruca vulgaris) and plantar warts (verruca plantaris). It is most effective on hyperkeratotic warts located on non-mucosal surfaces. The solution is typically prescribed after diagnosis by a healthcare provider to confirm the lesion is appropriate for topical podophyllotoxin treatment. It is not indicated for genital warts, facial warts, or moles, and should only be used on keratinized skin surfaces.

Dosage and direction

Apply twice daily (morning and evening) for 3 consecutive days, followed by a 4-day treatment-free interval. This one-week cycle may be repeated for up to 4 weeks or until the wart resolves, whichever comes first.

Preparation: Wash hands thoroughly. Cleanse the affected area with soap and water and dry completely. Soak the wart in warm water for 5 minutes and gently remove any loose tissue with a clean emery board or pumice stone.

Application: Using the supplied applicator, apply a minimal amount of solution sufficient to cover the wart surface. Avoid contact with surrounding healthy skin. Allow the solution to dry completely before covering with clothing or footwear. Wash hands immediately after application.

Precautions

• For external use only. Avoid contact with eyes, mucous membranes, and broken skin.
• Do not apply to irritated, bleeding, or recently shaved skin.
• Use with caution in patients with diabetes or peripheral vascular disease due to potential for impaired healing.
• Not recommended for use during pregnancy or while breastfeeding unless directed by a physician.
• Keep out of reach of children and pets.
• Discontinue use and consult a healthcare provider if excessive irritation, pain, or signs of infection develop.
• Do not cover with occlusive dressings unless specifically instructed by a healthcare provider.

Contraindications

• Hypersensitivity to podophyllotoxin or any component of the formulation
• Application to genital or perianal warts (requires specialist management)
• Use on facial warts or moles
• Patients with known blood dyscrasias or immunosuppression
• Use on birthmarks, unusual warts with hair growth, or pigmented lesions
• Children under 12 years of age (safety and efficacy not established)

Possible side effects

Most side effects are localized to the application site and typically mild to moderate in severity:

• Burning sensation (common)
• Erythema and inflammation (common)
• Pain or tenderness at application site
• Itching or pruritus
• Skin erosion or ulceration (if over-applied)
• Bleeding (rare, usually indicates over-application)
• Allergic contact dermatitis (uncommon)
• Systemic effects are rare with proper application but may include nausea or dizziness if large areas are treated

Drug interaction

No specific drug interactions have been documented with topical podophyllotoxin. However, concomitant use with other topical agents (especially those containing salicylic acid, cantharidin, or other keratolytics) may increase local irritation and should be avoided unless under medical supervision. Patients using immunosuppressive medications may experience altered response to treatment.

Missed dose

If a dose is missed, apply as soon as remembered unless it is nearly time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain the regular twice-daily schedule throughout the 3-day treatment cycle. The 4-day treatment-free interval should be maintained as directed.

Overdose

Overapplication may cause severe local reactions including pain, blistering, ulceration, and tissue necrosis. Systemic absorption through excessive application to large areas may cause nausea, vomiting, diarrhea, dizziness, peripheral neuropathy, or bone marrow suppression. In case of suspected overdose, remove any remaining medication by washing thoroughly with soap and water. Seek immediate medical attention if systemic symptoms occur or if large areas of skin are affected. Provide the product container to medical personnel.

Storage

Store at room temperature (15-30°C or 59-86°F). Keep the container tightly closed when not in use. Protect from light and moisture. Do not freeze. Discard any unused product 30 days after first opening. Do not transfer to other containers. Keep away from heat sources and open flames (product contains flammable components).

Disclaimer

This product is for external use only and should be used strictly as directed. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before using this product, especially if you have underlying medical conditions, are pregnant, or are breastfeeding. The information provided here is not exhaustive; refer to the official prescribing information for complete details. Results may vary based on individual factors including wart type, duration, and patient compliance.

Reviews

Clinical studies demonstrate complete clearance rates of 45-80% after 4 weeks of treatment, with higher efficacy observed in patients who comply with the prescribed application regimen. Dermatologists report satisfaction with Podowart’s precision application and predictable response profile. Patients appreciate the convenience of home treatment following professional diagnosis, though some note the importance of careful application to avoid irritation of surrounding skin. The treatment-free intervals are generally well-tolerated and allow for recovery of adjacent tissue.