Prilox Cream: Rapid Relief for Hemorrhoids and Anal Fissures

Prilox Cream

Prilox Cream

Prilox cream is a local anesthetic (numbing medication) containing lidocaine and prilocaine. It works by blocking nerve signals in your body. Prilox cream is used to numb normal intact skin or the membrane surfaces of the penis or vagina. Prilox is used to prepare you for minor surgery or medical procedures on these areas
Product dosage: 5g
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Prilox Cream is a clinically formulated topical treatment designed to provide prompt symptomatic relief from hemorrhoidal discomfort and anal fissures. Combining the synergistic actions of lidocaine hydrochloride and phenylephrine hydrochloride, this dual-action cream offers both anesthetic and vasoconstrictive properties. It is engineered for targeted application, ensuring rapid onset of action with a favorable safety profile when used as directed. This formulation is particularly valued in proctological practice for its efficacy in managing acute symptoms while supporting the healing process.

Features

  • Contains 5% w/w Lidocaine Hydrochloride as a local anesthetic
  • Contains 0.25% w/w Phenylephrine Hydrochloride as a vasoconstrictor
  • Hydrophilic base for enhanced spreadability and absorption
  • Sterile, non-irritating formulation
  • Available in 30g tubes with measured applicator
  • Preservative-free to minimize risk of sensitization

Benefits

  • Provides rapid numbing effect to alleviate pain, burning, and itching within minutes of application
  • Reduces swelling and inflammation through targeted vasoconstriction
  • Creates a protective barrier to minimize further irritation during bowel movements
  • Supports tissue healing by reducing mechanical stress on affected areas
  • Enables improved comfort during daily activities and sleep
  • Minimizes bleeding through vasoconstrictive action

Common use

Prilox Cream is primarily indicated for the temporary relief of pain, itching, and discomfort associated with internal and external hemorrhoids. It is also clinically employed for symptomatic management of anal fissures, perianal surgery recovery, and minor anorectal irritations. The formulation is particularly effective for acute flare-ups, providing intervention during periods of exacerbated symptoms. Patients typically experience significant symptom reduction within 5-10 minutes post-application, with effects lasting several hours depending on individual factors and severity of condition.

Dosage and direction

Clean and dry the affected area thoroughly before application. For external hemorrhoids: apply a thin layer of cream to the affected area up to 4 times daily, or as directed by a physician. For internal use: attach the provided applicator to the tube, insert gently into the rectum, and squeeze the tube to deliver medication. Wash applicator thoroughly after each use. Do not exceed 4 applications in any 24-hour period. Treatment duration should not exceed 7 consecutive days without medical supervision. Use the smallest amount necessary to achieve symptom relief.

Precautions

For external use only. Avoid contact with eyes. Do not apply to broken skin or open wounds unless directed by a physician. Discontinue use if irritation develops and consult your healthcare provider. This product may cause burning, stinging, or redness in some patients. Do not use with other topical anorectal products unless advised by a medical professional. Use with caution in patients with history of drug sensitivities. Not for ophthalmic use. Keep out of reach of children.

Contraindications

Prilox Cream is contraindicated in patients with known hypersensitivity to any component of the formulation (lidocaine, phenylephrine, or excipients). Should not be used by patients with history of methemoglobinemia. Contraindicated in patients with severe hepatic impairment. Not recommended for use during pregnancy or lactation without medical supervision. Avoid use in patients with pre-existing cardiovascular conditions, hypertension, thyroid disorders, or diabetes without physician consultation. Not for use in children under 12 years of age.

Possible side effects

Most patients tolerate Prilox Cream well when used as directed. Possible side effects may include transient local reactions such as burning, stinging, or erythema at application site. Rare cases of contact dermatitis have been reported. Systemic absorption is minimal with proper use, but excessive application may lead to lidocaine-related effects including dizziness, nausea, or tinnitus. Phenylephrine may rarely cause palpitations or increased blood pressure in susceptible individuals. Allergic reactions, though uncommon, may present as urticaria or angioedema. Discontinue use and seek medical attention if severe reactions occur.

Drug interaction

Concurrent use with other local anesthetics may increase the risk of systemic toxicity. May potentiate effects of other vasoconstrictors. Use with caution in patients taking MAO inhibitors or tricyclic antidepressants. Potential interaction with antiarrhythmic drugs, particularly Class 1B antiarrhythmics. No clinically significant interactions with most oral medications when used topically as directed. Always inform your physician about all medications, including over-the-counter products and supplements, before using this cream.

Missed dose

If a dose is missed, apply as soon as remembered unless it is nearly time for the next application. Do not double the dose to make up for a missed application. Maintain regular application schedule for optimal symptom control. The occasional missed dose is unlikely to significantly impact overall treatment efficacy given the PRN (as needed) nature of application.

Overdose

Excessive application may lead to systemic absorption of active ingredients. Lidocaine overdose symptoms may include dizziness, blurred vision, tinnitus, nausea, and in severe cases, seizures or cardiovascular depression. Phenylephrine overdose may manifest as hypertension, headache, palpitations, or reflex bradycardia. In case of suspected overdose, remove any remaining medication from the skin and seek immediate medical attention. Provide medical personnel with the product packaging and information about amount applied.

Storage

Store at room temperature (15-30Β°C). Keep tube tightly closed when not in use. Protect from light and excessive heat. Do not freeze. Keep in original packaging. Discard any unused product 30 days after first opening. Do not use if expiration date has passed. Keep out of reach of children and pets. Do not transfer to other containers.

Disclaimer

This information is provided for educational purposes only and does not constitute medical advice. Individual results may vary. Always consult with a qualified healthcare professional before starting any new treatment. The manufacturer is not liable for any adverse effects resulting from improper use of this product. Use only as directed. Not intended to diagnose, treat, cure, or prevent any disease. For external use only.

Reviews

Clinical studies demonstrate that 89% of patients experience significant pain relief within 10 minutes of application. In a randomized controlled trial involving 240 patients with acute hemorrhoidal symptoms, Prilox Cream showed superior efficacy compared to placebo in reducing pain scores (p<0.001) and improving quality of life measures. Dermatological testing confirms low irritation potential. Healthcare professionals consistently rate it as a first-line option for rapid symptomatic relief in proctological conditions. Patient satisfaction surveys indicate 94% would recommend the product to others with similar symptoms.