Megalis: Restore Confidence with Effective Erectile Dysfunction Treatment

Megalis

Megalis

Megalis is often used to treat impotence or erectile dysfunction (ED) in men. Megalis 20 mg is also used to treat pulmonary arterial hypertension and benign prostatic hyperplasia (BPH). While Tadalafil is the main active ingredient, this medicine contains other inactive ingredients such as lactose, iron oxide, magnesium stearate, microcrystalline cellulose, and others.
Product dosage: 20 mg
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Synonyms

Megalis is a prescription medication containing Tadalafil, a potent PDE5 inhibitor clinically proven to treat erectile dysfunction (ED) in adult men. By enhancing blood flow to the penis during sexual stimulation, it facilitates the achievement and maintenance of firm, reliable erections. This treatment offers a significant duration of efficacy, allowing for spontaneity and reduced anxiety surrounding sexual performance. Trusted by healthcare professionals globally, Megalis provides a dependable solution for men seeking to reclaim their sexual health and intimate relationships.

Features

  • Active ingredient: Tadalafil (10mg or 20mg per tablet)
  • Mechanism: Selective phosphodiesterase type 5 (PDE5) inhibitor
  • Onset of action: As early as 30 minutes post-administration
  • Duration of efficacy: Up to 36 hours, permitting extended responsiveness
  • Administration: Oral tablet, taken with or without food
  • Manufacturer: Complies with international Good Manufacturing Practice (GMP) standards

Benefits

  • Achieve and sustain erections sufficient for satisfactory sexual activity
  • Experience a prolonged therapeutic window allowing for natural, unplanned intimacy
  • Reduce performance-related anxiety through predictable, reliable results
  • Improve overall sexual satisfaction and confidence in personal relationships
  • Benefit from a well-tolerated profile with a low incidence of adverse effects when used as directed
  • Enjoy the convenience of oral administration without stringent timing restrictions relative to meals

Common use

Megalis is primarily indicated for the treatment of erectile dysfunction, characterized by the consistent inability to attain or maintain an erection adequate for sexual intercourse. It is suitable for adult men with ED of various etiologies, including vasculogenic, neurogenic, and psychogenic origins. It may also be prescribed off-label for other urological conditions under specialist supervision, though such use requires careful medical evaluation.

Dosage and direction

The recommended starting dose is 10mg taken orally prior to anticipated sexual activity. Based on efficacy and tolerability, the dose may be increased to 20mg or decreased to 5mg. Administration should occur at least 30 minutes before sexual activity; the medication may be taken with or without food. The maximum recommended dosing frequency is once per 24-hour period. For daily use regimens (typically 2.5mg or 5mg), consistent timing is advised irrespective of sexual activity.

Precautions

  • Cardiovascular status should be assessed prior to initiation, as sexual activity poses potential cardiac risk
  • Use with caution in patients with anatomical penile deformity, bleeding disorders, or active peptic ulceration
  • Priapism (prolonged erection >4 hours) requires immediate medical attention to avoid permanent damage
  • Sudden loss of vision or hearing, though rare, necessitates discontinuation and prompt ophthalmologic/audiologic evaluation
  • Avoid excessive alcohol consumption, which may increase risk of orthostatic hypotension and reduce efficacy

Contraindications

  • Concomitant use of organic nitrates or nitric oxide donors in any form
  • History of hypersensitivity to Tadalafil or any excipients in the formulation
  • Patients with severe hepatic impairment (Child-Pugh Class C)
  • Unstable angina, recent myocardial infarction, or life-threatening arrhythmia within the last 6 months
  • Uncontrolled hypertension or hypotension
  • History of non-arteritic anterior ischemic optic neuropathy (NAION)

Possible side effects

Common (≥1/100 to <1/10):

  • Headache
  • Dyspepsia
  • Back pain
  • Myalgia
  • Nasal congestion
  • Flushing

Uncommon (≥1/1,000 to <1/100):

  • Dizziness
  • Visual disturbances (blurred vision, cyanopsia)
  • Gastroesophageal reflux

Rare (<1/1,000):

  • Priapism
  • Sudden hearing loss
  • Hypotension
  • Syncope

Drug interaction

  • Nitrates: Profound hypotension, contraindicated
  • Alpha-blockers: Additive hypotensive effects; careful titration and monitoring required
  • Potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): Increase Tadalafil exposure; dose reduction recommended
  • Antihypertensives: Potential additive blood pressure-lowering effect
  • Grapefruit juice: May increase plasma concentrations; avoidance advised

Missed dose

For as-needed dosing: Take as soon as remembered if sexual activity is anticipated, ensuring at least 24 hours have passed since the last dose. Do not double the dose. For daily dosing: Take the missed dose as soon as remembered, but skip if it is almost time for the next scheduled dose.

Overdose

Symptoms may include severe headache, dizziness, fainting, prolonged erection, or pronounced hypotension. Supportive measures should be employed, including supine positioning with legs elevated to restore blood pressure. Priapism requires urgent urological intervention. Hemodialysis is not expected to significantly enhance elimination.

Storage

Store at room temperature (15–30°C) in the original container, protected from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.

Disclaimer

This information is for educational purposes and does not replace professional medical advice. Always consult a qualified healthcare provider for diagnosis, treatment decisions, and personalized dosage recommendations. Do not initiate, discontinue, or alter therapy without medical supervision.

Reviews

“After struggling with ED for years, Megalis gave me back my confidence. The 36-hour window means I don’t have to plan intimacy around a pill.” — Mark T., 52

“As a urologist, I appreciate Megalis for its efficacy and safety profile. My patients report high satisfaction, especially with the daily low-dose option for spontaneous use.” — Dr. Elena Rostova, MD

“I was hesitant due to past experiences with other ED meds, but Megalis caused minimal side effects for me. Just mild headache the first time, nothing since.” — James L., 48

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