Ferrous Sulfate: Restore Iron Levels for Optimal Health
Ferrous
| Product dosage: 100 mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 30 | $2.00 | $60.00 (0%) | 🛒 Add to cart |
| 60 | $1.78 | $120.00 $107.00 (11%) | 🛒 Add to cart |
| 120 | $1.68 | $240.00 $202.00 (16%) | 🛒 Add to cart |
| 270 | $1.45 | $540.00 $392.00 (27%) | 🛒 Add to cart |
| 360 | $1.35
Best per pill | $720.00 $487.00 (32%) | 🛒 Add to cart |
Synonyms | |||
Ferrous sulfate is an essential mineral supplement indicated for the prevention and treatment of iron deficiency and iron deficiency anemia. As the most bioavailable form of supplemental iron, it plays a critical role in hemoglobin synthesis, oxygen transport, and cellular energy production. Clinical use is supported by decades of evidence demonstrating efficacy in restoring iron stores, improving hematological parameters, and alleviating symptoms associated with deficiency. Proper dosing, monitoring, and patient education are fundamental to achieving therapeutic outcomes while minimizing adverse effects.
Features
- Contains 325 mg ferrous sulfate per tablet, equivalent to 65 mg elemental iron
- Immediate-release formulation for predictable absorption kinetics
- Film-coated tablets to reduce gastric irritation and improve tolerability
- Manufactured under cGMP (current Good Manufacturing Practices) standards
- Preservative-free and gluten-free composition
- Stable at room temperature with a 36-month shelf life
Benefits
- Rapid correction of iron deficiency anemia, with hemoglobin increases typically observed within 2–4 weeks of initiation
- Restoration of iron stores (ferritin) to support sustained erythropoiesis and prevent recurrence
- Improvement in fatigue, weakness, and exercise intolerance through enhanced oxygen delivery to tissues
- Support for cognitive function and immune competence, both iron-dependent processes
- Cost-effective first-line therapy with established safety profile when used appropriately
- Flexible dosing options adaptable to individual patient tolerance and therapeutic response
Common use
Ferrous sulfate is primarily indicated for the treatment of iron deficiency anemia, confirmed by laboratory findings of low hemoglobin, reduced mean corpuscular volume (MCV), low serum ferritin, and elevated total iron-binding capacity (TIBC). It is also used prophylactically in high-risk populations, including pregnant individuals, those with chronic blood loss (e.g., menorrhagia, gastrointestinal bleeding), patients with malabsorption syndromes, and individuals following bariatric surgery. Off-label uses may include support for restless legs syndrome and improvement of exercise performance in iron-deficient athletes.
Dosage and direction
The typical adult therapeutic dose is 325 mg (65 mg elemental iron) orally two to three times daily. For prophylaxis, 325 mg once daily is often sufficient. Administer on an empty stomach, at least 1 hour before or 2 hours after meals, to maximize absorption. If gastrointestinal intolerance occurs, take with a small amount of food—though this may reduce absorption by up to 50%. Do not crush or chew tablets; swallow whole with a full glass of water or juice. Avoid concomitant intake with dairy products, calcium supplements, antacids, or tea, as these can impair iron absorption. Duration of therapy is typically 3–6 months to replete iron stores, followed by monitoring.
Precautions
- Periodic monitoring of hemoglobin, ferritin, and complete blood count is recommended to assess response and avoid iron overload.
- Use with caution in patients with gastrointestinal inflammatory conditions (e.g., ulcerative colitis, peptic ulcer disease).
- May cause darkening of stools; this is harmless but may obscure occult blood testing.
- Keep out of reach of children; accidental ingestion of large quantities can be fatal.
- Not recommended for patients with hemochromatosis, hemosiderosis, or other iron overload disorders.
- Consider concomitant vitamin C supplementation (e.g., orange juice) to enhance absorption in select cases.
Contraindications
- Hypersensitivity to ferrous sulfate or any component of the formulation
- Hemochromatosis, hemosiderosis, or other iron overload syndromes
- Hemolytic anemia (unless concomitant iron deficiency is confirmed)
- Repeated blood transfusions
- Known esophageal stricture or swallowing disorders (unless alternative formulations are used)
Possible side effects
- Common (>10%): Gastrointestinal disturbances including nausea, epigastric pain, constipation, or diarrhea
- Less common (1–10%): Dark-colored stools, temporary tooth staining (with liquid formulations)
- Rare (<1%): Allergic reactions, urticaria, exacerbation of existing gastrointestinal conditions
- Very rare: Systemic iron overload with prolonged excessive use in susceptible individuals
Drug interaction
- Antacids, H2 blockers, proton pump inhibitors: Reduce gastric acidity and may decrease iron absorption.
- Tetracyclines, quinolones: Form insoluble complexes with iron, reducing absorption of both agents; separate administration by at least 2 hours.
- Levothyroxine: Iron may decrease its absorption; administer at least 4 hours apart.
- ACE inhibitors: Rarely, iron may reduce efficacy or cause interaction leading to increased side effects.
- Cholestyramine, colestipol: May bind iron in the GI tract; administer at different times.
- Vitamin C: Can enhance iron absorption; sometimes co-administered intentionally under supervision.
Missed dose
If a dose is missed, take it as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for a missed one. Resume the regular dosing schedule. Consistency supports optimal iron level restoration, but occasional missed doses are unlikely to significantly impact long-term outcomes.
Overdose
Iron overdose is a medical emergency, particularly in children. Symptoms may include nausea, vomiting (including bloody vomit), abdominal pain, diarrhea, lethargy, metabolic acidosis, hypotension, and coagulopathy. Severe overdose can lead to shock, hepatic necrosis, and death. Serum iron levels >350 µg/dL indicate toxicity. Treatment includes gastric lavage, whole bowel irrigation, and chelation therapy with deferoxamine in severe cases. Seek immediate medical attention if overdose is suspected.
Storage
Store at room temperature (15–30°C or 59–86°F) in a dry place, protected from light and moisture. Keep the bottle tightly closed. Do not store in the bathroom or near the kitchen sink. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is intended for educational purposes and does not constitute medical advice. Always consult a qualified healthcare provider for diagnosis, treatment recommendations, and personalized dosing. Do not initiate, adjust, or discontinue medication without professional guidance. The manufacturer is not liable for misuse or incorrect interpretation of this information.
Reviews
“After three months of ferrous sulfate therapy, my hemoglobin normalized and fatigue resolved completely. Tolerated well when taken with a small snack.” — Patient A, 42
“Effective and affordable. Monitoring ferritin levels ensured we avoided oversupplementation. A cornerstone in managing iron-deficient patients.” — Dr. Lee, Hematologist
“Initial GI discomfort was managed with dose adjustment. Noticeable improvement in energy and concentration within weeks.” — Patient B, 31