Cialis Daily for Sustained Erectile Function Management
Cialis
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| Product dosage: 2.5mg | |||
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| Product dosage: 20mg | |||
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| Product dosage: 5mg | |||
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Synonyms | |||
Similar products
Cialis Daily (tadalafil) is a prescription phosphodiesterase type 5 (PDE5) inhibitor formulated for daily administration to manage erectile dysfunction (ED). Unlike on-demand dosing, this low-dose regimen provides continuous therapeutic plasma concentrations, allowing for spontaneous sexual activity without the need for timing medication around anticipated events. It represents a strategic approach for men seeking consistent readiness and is particularly suited for those with frequent sexual activity or who prefer the convenience of a daily routine. Its efficacy is well-established in clinical literature, offering a reliable option within the broader ED therapeutic landscape.
Features
- Active Pharmaceutical Ingredient: Tadalafil 2.5 mg or 5 mg
- Pharmacological Class: Phosphodiesterase type 5 (PDE5) inhibitor
- Administration: Oral, once daily
- Onset of Action: Allows for spontaneous activity; steady-state plasma concentration is achieved within 5 days
- Duration of Effect: 24-hour coverage due to ~17.5-hour half-life at steady state
- Bioavailability: Approximately 36-42%, not significantly affected by food
- Excretion: Primarily hepatic metabolism (mainly CYP3A4), fecal elimination
Benefits
- Enables spontaneous sexual activity without the need to plan medication timing.
- Provides continuous therapeutic coverage, reducing performance anxiety associated with on-demand dosing.
- Effective in treating erectile dysfunction of various etiologies (vasculogenic, neurogenic, psychogenic).
- May improve endothelial function beyond its primary indication.
- Supports a more natural and integrated approach to sexual health within daily life.
- Consistent low-dose regimen may be associated with a favorable side effect profile for some patients.
Common use
Cialis Daily is indicated for the management of erectile dysfunction, a condition characterized by the consistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It is prescribed for adult men and is used regardless of the underlying etiology, which can include vascular disease, diabetes mellitus, radical prostatectomy, spinal cord injury, or psychological factors. It is not intended for use by women, children, or adolescents.
Dosage and direction
The recommended starting dose for Cialis Daily is 2.5 mg taken orally once per day, at approximately the same time each day. Based on efficacy and tolerability, the dose may be increased to 5 mg once daily. It may be taken with or without food. Sexual activity is permissible at any time following initiation of daily dosing, though maximum efficacy at a given dose is achieved after 5 days of continuous use to reach steady-state concentration. The medication does not automatically produce an erection; sexual stimulation is required.
Precautions
Prior to initiation, a thorough medical history and physical examination should be conducted to diagnose ED, assess cardiovascular health, and determine appropriateness of therapy. Patients should be advised that Cialis Daily offers no protection against sexually transmitted diseases. Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie’s disease), conditions predisposing to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia), or severe hepatic impairment (Child-Pugh Class C). Patients with cardiovascular disease should be assessed for exercise tolerance, as sexual activity poses a cardiac risk. PDE5 inhibitors, including tadalafil, have mild systemic vasodilatory properties.
Contraindications
Cialis Daily is contraindicated in patients:
- Using any form of organic nitrates or nitric oxide donors (e.g., nitroglycerin, isosorbide mononitrate), either regularly or intermittently, due to the risk of profound hypotension.
- With a known hypersensitivity to tadalafil or any excipient in the formulation.
- With severe hepatic impairment.
- Who have experienced non-arteritic anterior ischemic optic neuropathy (NAION) in one eye while taking any PDE5 inhibitor.
Possible side effect
The following adverse reactions have been reported and are generally mild or moderate in nature:
- Headache
- Dyspepsia
- Back pain
- Myalgia
- Nasopharyngitis
- Flushing
- Nasal congestion Rare but serious side effects include:
- Priapism (prolonged and painful erection lasting more than 4 hours)
- Sudden hearing loss
- Tinnitus
- Vision changes, including NAION
- Cardiovascular events (e.g., angina, myocardial infarction) in patients with pre-existing cardiovascular risk
Drug interaction
Concomitant use with nitrates is absolutely contraindicated. Potent inhibitors of the cytochrome P450 3A4 (CYP3A4) isoenzyme (e.g., ketoconazole, ritonavir, clarithromycin) can increase tadalafil exposure; a dose reduction should be considered. Alpha-blockers (e.g., doxazosin, tamsulosin) may potentiate the blood-pressure-lowering effects; concomitant use should be approached with caution and only if the patient is stable on their alpha-blocker therapy. Blood-pressure-lowering effects may also be additive when taken with antihypertensives. Alcohol in combination with tadalafil may increase the potential for orthostatic signs and symptoms.
Missed dose
If a dose is missed, it should be taken as soon as remembered on that day. If it is not remembered until the next day, the missed dose should be skipped, and the regular dosing schedule resumed. Do not take a double dose to make up for a missed one.
Overdose
In cases of suspected overdose, standard supportive measures should be employed. Expected effects would be an extension of the drug’s vasodilatory properties, including severe headache, flushing, dizziness, and potentially significant hypotension. Hemodialysis is not expected to accelerate clearance as tadalafil is highly protein-bound.
Storage
Store at room temperature (20°C to 25°C or 68°F to 77°F), with excursions permitted between 15°C and 30°C (59°F to 86°F). Keep in the original container to protect from light and moisture. Keep out of reach of children and pets.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here.
Reviews
“Switching to the daily low-dose regimen was a game-changer for my patient with performance anxiety. The ability to be spontaneous removed the psychological pressure that was a significant component of his ED.” – Urologist, Massachusetts “Provides a steady-state option that is highly valued by patients in stable relationships who desire frequency and predictability. The 5 mg dose is generally well-tolerated in my clinical experience.” – Andrologist, California “An important tool in our arsenal. It’s particularly beneficial for patients who find the timing of on-demand PDE5 inhibitors to be a barrier to a satisfactory sex life.” – General Practitioner, Texas