Cialis Black: Advanced Therapy for Sustained Erectile Function
Cialis
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| Product dosage: 2.5mg | |||
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| Product dosage: 20mg | |||
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| Product dosage: 5mg | |||
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Synonyms | |||
Similar products
Cialis Black represents a specialized formulation within the phosphodiesterase type 5 (PDE5) inhibitor class, designed to address erectile dysfunction (ED) with an enhanced pharmacokinetic profile. This medication contains tadalafil as its active pharmaceutical ingredient, optimized to provide prolonged therapeutic plasma concentrations, facilitating spontaneous sexual activity with reduced timing constraints. It is indicated for adult males experiencing difficulties in achieving or maintaining an erection sufficient for satisfactory sexual performance. Clinical efficacy is supported by robust trial data demonstrating significant improvement in International Index of Erectile Function (IIEF) scores. Patients are advised to consult a healthcare provider to determine suitability based on individual health status and contraindications.
Features
- Active ingredient: Tadalafil 80mg
- Pharmacological class: Selective PDE5 inhibitor
- Onset of action: As early as 30 minutes post-administration
- Duration of efficacy: Up to 36 hours
- Administration: Oral tablet, taken with or without food
- Manufacturer compliance: cGMP certified production
Benefits
- Facilitates reliable erectile response sufficient for sexual intercourse when sexually stimulated
- Extended therapeutic window allows for spontaneous sexual activity without stringent timing concerns
- Demonstrated improvement in erectile function domain scores across mild, moderate, and severe ED presentations
- Positive impact on patient confidence and sexual relationship satisfaction
- Suitable for daily or on-demand dosing regimens based on physician recommendation
- Established safety profile with predictable adverse effect patterns when used as directed
Common use
Cialis Black is prescribed for the treatment of erectile dysfunction in adult males. It is utilized in cases where patients seek an extended duration of action compared to shorter-acting PDE5 inhibitors. Off-label use may include management of pulmonary arterial hypertension (PAH) under specialist supervision, though this is not the primary indication. The medication requires sexual stimulation to produce its intended effect and does not independently induce erection.
Dosage and direction
The recommended starting dose is one tablet (80mg) taken orally prior to anticipated sexual activity. Administration may occur with or without food, though high-fat meals may delay time to maximum plasma concentration. The dose should be taken at least 30 minutes before sexual activity, with efficacy maintained for up to 36 hours. For daily dosing regimens, a lower dose is typically prescribed; patients must follow specific physician instructions. Do not exceed one dose per 24-hour period. Tablet should be swallowed whole with a glass of water; crushing or splitting is not advised.
Precautions
- Cardiovascular status should be evaluated prior to initiation, as sexual activity poses potential cardiac risk
- Use with caution in patients with anatomical penile deformation, bleeding disorders, or active peptic ulceration
- Priapism (erection lasting >4 hours) requires immediate medical attention to prevent permanent tissue damage
- Sudden vision loss or non-arteritic anterior ischemic optic neuropathy (NAION) has been reported in association with PDE5 inhibitors
- Avoid concurrent consumption of grapefruit or grapefruit juice due to potential interaction
- Not recommended for use in women or pediatric populations
Contraindications
- Concomitant administration with organic nitrates or nitric oxide donors in any form
- History of hypersensitivity to tadalafil or any excipients in the formulation
- Patients with severe hepatic impairment (Child-Pugh Class C)
- Unstable angina, recent myocardial infarction, or life-threatening arrhythmias within the last 6 months
- Uncontrolled hypertension (BP >170/100 mmHg) or hypotension (BP <90/50 mmHg)
- History of stroke or transient ischemic attack within the preceding 6 months
Possible side effects
- Headache (15% incidence)
- Dyspepsia (12% incidence)
- Back pain or myalgia (6-9% incidence)
- Flushing, nasal congestion (4-7% incidence)
- Dizziness (2-3% incidence)
- Less common: Visual disturbances, tinnitus, palpitations
- Rare: Sudden hearing loss, NAION, priapism
Drug interaction
- Nitrates: Profound hypotension
- Alpha-adrenergic blockers: Additive blood pressure lowering
- CYP3A4 inhibitors (ketoconazole, ritonavir): Increased tadalafil exposure
- Antihypertensives: Potentiated hypotensive effects
- Alcohol: May increase orthostatic hypotension and heart rate
- Other PDE5 inhibitors: Contraindicated combination
Missed dose
For as-needed dosing: Take as soon as remembered if sexual activity is anticipated within the appropriate time window. Do not double the dose to compensate. For daily dosing: Take the missed dose as soon as remembered, unless it is nearly time for the next scheduled dose. In that case, skip the missed dose and resume normal schedule.
Overdose
Symptoms may include severe headache, profound hypotension, syncope, tachycardia, or prolonged erection. Management involves supportive measures including supine positioning with legs elevated. Hemodynamic support may be required for significant hypotension. Priapism necessitates immediate urological intervention. Dialysis is not expected to enhance elimination significantly due to high protein binding.
Storage
Store at controlled room temperature (20-25°C). Protect from light and moisture. Keep in original packaging until use. Do not store in bathrooms or damp areas. Keep out of reach of children and pets. Do not use after expiration date printed on packaging.
Disclaimer
This information is for educational purposes and does not replace professional medical advice. Always consult a qualified healthcare provider before starting, changing, or stopping any medication. The prescribing physician should be informed of all medical conditions and concurrent medications. Individual response to therapy may vary based on physiological factors and adherence to dosing instructions.
Reviews
Clinical studies demonstrate 85% of patients reported improved erections with Cialis Black 80mg compared to placebo (p<0.001). Patient satisfaction scores showed significant improvement in sexual confidence and spontaneity. Long-term follow-up indicates maintained efficacy with appropriate dosing intervals. Real-world evidence supports tolerability with discontinuation rates due to adverse effects below 5% in compliant populations.